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Buy Flibanserin (addyi) Pills Online

The article below provides a descriptive summary of Flibanserin, shares an overview of its application and analyses diversified side effects, as well as includes useful information for every patient who plans to use it.

What is addyi?

Flibanserin represents a modulator of 5-HT receptor, which is applied to treat specific premenopausal female patients, who have generalized, acquired, hypoactive sexual desire disorder (HSDD).

Flibanserin is among the first medications that have received FDA approval for treatment of premenopausal women from hypoactive sexual desire disorder (HSDD) back in August 2015. Initially, this medication was acting like an antidepressant, however with time it didn’t result in sufficient efficacy during various trials and was subsequently modified to become a hypoactive sexual disorder treatment. The mechanism of Flibanserin action is related to its close affinity with 5-HTA1 and 5-HTA2 receptors, exhibiting agonist action on 5-HTA1 and antagonist on 5-HTA2, which cause reduction of serotonin levels in the brain, while increasing dopamine and norepinephrine neurotransmitters amount.

Mechanism of Flibanserin Action

Apart from abovementioned affinity of Flibanserin for serotonin receptors inside the brain, it also binds similarly to both 5-HT1A and 5-HT2A receptors. However, in cases of increased levels of brain 5-HT (i.e., during stress), Flibanserin may inhabit 5-HT2A receptors in a bigger proportion comparing to 5-HT(1A) receptors. In addition, Flibanserin may also antagonize D4 (dopamine) receptors as well as 5-HT2B and 5-HTB2C in a moderate manner. Its influence on neurotransmitter receptors can cause serotonin levels to reduce, while increasing norepinephrine and dopamine levels, which in the end results in positive results from treatment.

Addyi Side Effects

Flibanserin may result in the following side effects:

  • CNS depression
  • Sedation
  • Somnolence
  • Insomnia
  • Fatigue
  • Dryness of mouth

Patients taking Flibanserin should abstain from driving or engaging in other types of activities that require complete alertness for minimum of 6 hours after administering Flibanserin. Abstain from using CNS depressants like opioids, diphenhydramine, benzodiazepines and hypnotics together with Flibanserin. Flibanserin alone can result in syncope as well as hypotension.

Various studies on mice have confirmed dose-associated increase in cases of malignant mammary tumors among female mice (exposure levels 3 and 10 times higher than the suggested clinical dose). This effect was not observed among male mice or in male/female rats.

It is highly advised that you purchase addyi only in reputable and verified pharmacies and with doctor’s prescription. Your healthcare practitioner will surely suggest you the most suitable pharmacy, however you can also do your own research online in order to find the verified online drugstores. Moreover, you can save your searching time and purchase Flibanserin from our pharmacy (name of pharmacy), as it has got a long history of working in pharmaceutical market and has already earned a very good reputation among clients and companions.

author: Tony Olivier, Pharm D.